Projects per year
Projects
- 2 Active
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Impact of Inflammatory Cytokines on ER-Mitochondria Crosstalk and Proinsulin Folding in Beta Cells
Arunagiri, A. (PI) & Bradshaw, P. C. (PI)
9/1/25 → 8/31/26
Project: Research project
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Proinsulin Proteostasis and ER-Mitochondrial Crosstalk in Beta Cell Glucolipotoxicity
Arunagiri, A. (PI) & Bradshaw, P. C. (CoI)
7/1/25 → 9/30/26
Project: Research project
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Unraveling C-Peptide’s Role in MIDY: A Structural Perspective
Ranganathan, S., Ghaffarian Zavarzadeh, P., Dick, K., Bishop, D., Kilgore, P. & Arunagiri, A., Feb 2 2026, In: ACS Omega. 11, 6, p. 9890–9901 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Exploring proinsulin proteostasis: Insights into beta cell health and diabetes
Ghaffarian Zavarzadeh, P., Panchal, K., Bishop, D., Gilbert, E., Trivedi, M., Kee, T., Ranganathan, S. & Arunagiri, A., Mar 4 2025, In: Frontiers in Molecular Biosciences. 12Research output: Contribution to journal › Article › peer-review
Open Access -
Limiting ER-associated degradation capacity triggers acute and chronic effects on insulin biosynthesis
Arunagiri, A., Haataja, L., Alam, M., Gleason, N. F., Mastroianni, E., Cheng, C.-Y., Bazzi, S., Knupp, J., Metawea, I., Hassan, A., Larkin, D., Fang, D., Tsai, B., Qi, L. & Arvan, P., Nov 18 2025, In: Journal of Clinical Investigation. 136, 2, p. 1-12 12 p., e187341.Research output: Contribution to journal › Article › peer-review
Open Access -
Quantification of Folded and Misfolded Proinsulin Forms Using Nonreducing SDS-PAGE and Proinsulin-Specific Immunoblotting
Arunagiri, A., Jang, I., Itkin-Ansari, P., Kaufman, R. J. & Arvan, P., Jun 5 2025, In: Bio-protocol. 15, 11Research output: Contribution to journal › Article › peer-review
Open Access -
Recessive TMEM167A variants cause neonatal diabetes, microcephaly and epilepsy syndrome
Virgilio, E., Tielens, S., Bonfield, G., Nian, F.-S., Sawatani, T., Vinci, C., Govier, M., Montaser, H., Lartigue, R., Arunagiri, A., Liboz, A., Natividade Da Silva, F., Lytrivi, M., Papadopoulou, T., Wakeling, M. N., Russ-Silsby, J., Bowman, P., Johnson, M. B., Laver, T. W. & Piron, A. & 26 others, , Sep 9 2025, In: Journal of Clinical Investigation. 135, 22, p. 1-15 15 p., e195756.Research output: Contribution to journal › Article › peer-review
Open Access