Michael D. Kruppa

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Genetic Characterization of Phosphomannan Biosynthesis in C. auris
Kruppa, M. D. (PI) & Ma, Z. (CoPI)
National Institutes of Health, National Institute of Allergy and Infectious Disease
3/12/21 → 2/29/24
Project: Research project
Genetics of trans-kingdom interactions between Candida and bacteria
Kruppa, M. D. (PI), Stuffle, D. (CoI), Magnussen, J. (CoI), Watson, J. (CoI) & Cameron, A. (CoI)
NIH
6/15/14 → 5/31/18
Project: Research project

36 Article
9 Poster
5 Presentation
3 Paper
More

A glycan-based adjuvant expands the breadth and duration of protection of mRNA-based vaccines
Jena, K. K., Qu, P., Baracco, L., Saghaei, S., Keerti, Allahyari, Z., Boehmer, D., Mitchell, M., Dillen, C. A., Li, H. Y., Liu, E., Poli, V., Dufies, O., Hoytema van Konijnenburg, D. P., Spreafico, R., Bi, C., Hall, R., Kruppa, M. D., Ma, Z. & Gravitte, A. & 15 others, Lowman, D. W., Ensley, H. E., Marty, P., Boyer, L., Collomp, R., Williams, D. L., Ma, V. P. Y., Lee, P. Y., Nigrovic, P. A., Karp, J. M., Elledge, S. J., Wesemann, D. R., Wu, Y., Frieman, M. & Zanoni, I., Jun 2026, In: Nature Immunology. 27, 6, p. 1130-1144 15 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Candida albicans glucan/glycogen complexes promote synergistic inflammation via TLR2 and Mincle
Ozment, T., Kruppa, M., Lewis, N. & Williams, D., Jan 1 2025.
Research output: Contribution to conference › Poster
Candida Albicans Glucan-Glycogen Cell Wall Complex: A Novel PAMP that plays an important role in regulation Fungal Host-Pathogen Interactions
Ozment, T., Ma, Z., Kruppa, M. & Hopke, A., Jun 1 2025.
Research output: Contribution to conference › Poster › peer-review
Dectin-1 stimulating β-glucans inhibit Chlamydia infections both in vitro and in vivo
Kintner, J., Callaghan, M., Bulawa, L., Chu, A., Ma, Z., Williams, D. L., Schoborg, R. V., Kruppa, M. D. & Hall, J. V., 2025, In: Pathogens and Disease. 83, ftaf002.
Research output: Contribution to journal › Article › peer-review

Open Access
Fungal glycogen contributes to Candida albicans β-(1→3)-glucan masking, Dectin-1-dependent cytokine release, and oral commensalism
Miao, J., Sekar, J., Hopke, A., Kruppa, M., Ozment, T., Williams, D., Swidergall, M. & Peters, B., Jan 1 2025.
Research output: Contribution to conference › Presentation

Michael D. Kruppa

Projects

Genetic Characterization of Phosphomannan Biosynthesis in C. auris

Genetics of trans-kingdom interactions between Candida and bacteria

Research output

A glycan-based adjuvant expands the breadth and duration of protection of mRNA-based vaccines

Candida albicans glucan/glycogen complexes promote synergistic inflammation via TLR2 and Mincle

Candida Albicans Glucan-Glycogen Cell Wall Complex: A Novel PAMP that plays an important role in regulation Fungal Host-Pathogen Interactions

Dectin-1 stimulating β-glucans inhibit Chlamydia infections both in vitro and in vivo

Fungal glycogen contributes to Candida albicans β-(1→3)-glucan masking, Dectin-1-dependent cytokine release, and oral commensalism