TY - JOUR
T1 - Alternating Extremely Low Frequency Magnetic Field Increases Turnover of Dopamine and Serotonin in Rat Frontal Cortex
AU - Sieroń, Aleksander
AU - Labus, Łukasz
AU - Nowak, Przemysław
AU - Cieślar, Grzegorz
AU - Brus, Halina
AU - Durczok, Artur
AU - Zagził, Tomasz
AU - Kostrzewa, Richard M.
AU - Brus, Ryszard
PY - 2004/9/1
Y1 - 2004/9/1
N2 - The aim of this study was to evaluate the influence of an extremely low frequency sinusoidal magnetic field (ELF MF) with frequency of 10 Hz and intensity of 1.8-3.8 mT on the levels of the biogenic amines dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), 3-methoxytyramine (3-MT), 5-hydroxytryptamine (5-HT), 5-hydroxyindolacetic acid (5-HIAA), and noradrenaline (NA), as well as on DA and 5-HT turnover in corpus striatum and frontal cortex of adult male Wistar rats. We found that ELF MF exposure for 14 days, 1 h daily, did not influence the level of the examined biogenic amines and metabolites, but increased the rate of synthesis (turnover) of DA and 5-HT in rat frontal cortex as compared to control, sham exposed rats. On the basis of the present results and our previous findings, extremely low frequency magnetic field (ELF MF) exposure has been found to alter both turnover and receptor reactivity of monoaminergic systems, as well as some behaviors induced by these systems or their agonists and antagonists.
AB - The aim of this study was to evaluate the influence of an extremely low frequency sinusoidal magnetic field (ELF MF) with frequency of 10 Hz and intensity of 1.8-3.8 mT on the levels of the biogenic amines dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), 3-methoxytyramine (3-MT), 5-hydroxytryptamine (5-HT), 5-hydroxyindolacetic acid (5-HIAA), and noradrenaline (NA), as well as on DA and 5-HT turnover in corpus striatum and frontal cortex of adult male Wistar rats. We found that ELF MF exposure for 14 days, 1 h daily, did not influence the level of the examined biogenic amines and metabolites, but increased the rate of synthesis (turnover) of DA and 5-HT in rat frontal cortex as compared to control, sham exposed rats. On the basis of the present results and our previous findings, extremely low frequency magnetic field (ELF MF) exposure has been found to alter both turnover and receptor reactivity of monoaminergic systems, as well as some behaviors induced by these systems or their agonists and antagonists.
KW - ELF magnetic field
KW - biogenic amine level
KW - biogenic amine synthesis
KW - brain
UR - https://dc.etsu.edu/etsu-works/18658
UR - https://doi.org/10.1002/bem.20011
U2 - 10.1002/bem.20011
DO - 10.1002/bem.20011
M3 - Article
VL - 25
JO - Bioelectromagnetics
JF - Bioelectromagnetics
ER -