Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways

Fatma Saaoud; Lu Liu; Keman Xu; Ramon Cueto; Ying Shao; Yifan Lu; Yu Sun; Nathaniel W. Snyder; Sheng Wu; Ling Yang; Yan Zhou; David L. Williams; Chuanfu Li; Laisel Martinez; Roberto I. Vazquez-Padron; Huaqing Zhao; Xiaohua Jiang; Hong Wang; Xiaofeng Yang

doi:10.1172/jci.insight.158183

Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways

Fatma Saaoud
, Lu Liu
, Keman Xu
, Ramon Cueto
, Ying Shao
, Yifan Lu
, Yu Sun
, Nathaniel W. Snyder
, Sheng Wu
, Ling Yang
, Yan Zhou
, David L. Williams
, Chuanfu Li
, Laisel Martinez
, Roberto I. Vazquez-Padron
, Huaqing Zhao
, Xiaohua Jiang
, Hong Wang
, Xiaofeng Yang

Department of Surgery

Lewis Katz School of Medicine
Fox Chase Cancer Center
University of Miami Leonard M. Miller School of Medicine

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	e158183
Journal	JCI Insight
Volume	8
Issue number	1
DOIs	https://doi.org/10.1172/jci.insight.158183
State	Published - Jan 10 2023

ASJC Scopus Subject Areas

General Medicine

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10.1172/jci.insight.158183

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Saaoud, F., Liu, L., Xu, K., Cueto, R., Shao, Y., Lu, Y., Sun, Y., Snyder, N. W., Wu, S., Yang, L., Zhou, Y., Williams, D. L., Li, C., Martinez, L., Vazquez-Padron, R. I., Zhao, H., Jiang, X., Wang, H., & Yang, X. (2023). Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways. JCI Insight, 8(1), Article e158183. https://doi.org/10.1172/jci.insight.158183

Saaoud, F, Liu, L, Xu, K, Cueto, R, Shao, Y, Lu, Y, Sun, Y, Snyder, NW, Wu, S, Yang, L, Zhou, Y, Williams, DL , Li, C, Martinez, L, Vazquez-Padron, RI, Zhao, H, Jiang, X, Wang, H & Yang, X 2023, 'Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways', JCI Insight, vol. 8, no. 1, e158183. https://doi.org/10.1172/jci.insight.158183

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title = "Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways",

author = "Fatma Saaoud and Lu Liu and Keman Xu and Ramon Cueto and Ying Shao and Yifan Lu and Yu Sun and Snyder, \{Nathaniel W.\} and Sheng Wu and Ling Yang and Yan Zhou and Williams, \{David L.\} and Chuanfu Li and Laisel Martinez and Vazquez-Padron, \{Roberto I.\} and Huaqing Zhao and Xiaohua Jiang and Hong Wang and Xiaofeng Yang",

note = "Publisher Copyright: {\textcopyright} 2023, Saaoud et al. This is an open access article published under the terms of the Creative Commons Attribution 4.0 International License.",

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doi = "10.1172/jci.insight.158183",

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AU - Saaoud, Fatma

AU - Liu, Lu

AU - Xu, Keman

AU - Cueto, Ramon

AU - Shao, Ying

AU - Lu, Yifan

AU - Sun, Yu

AU - Snyder, Nathaniel W.

AU - Wu, Sheng

AU - Yang, Ling

AU - Zhou, Yan

AU - Williams, David L.

AU - Li, Chuanfu

AU - Martinez, Laisel

AU - Vazquez-Padron, Roberto I.

AU - Zhao, Huaqing

AU - Jiang, Xiaohua

AU - Wang, Hong

AU - Yang, Xiaofeng

PY - 2023/1/10

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Aorta- and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways

ASJC Scopus Subject Areas

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