Chemically induced dimerization of dihydrofolate reductase by a homobifunctional dimer of methotrexate

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)313-321
Number of pages9
JournalChemistry and Biology
Volume7
Issue number5
DOIs
StatePublished - May 1 2000

ASJC Scopus Subject Areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

Keywords

  • Affinity modulation
  • Chemically induced dimerization
  • Dihydrofolate reductase
  • Dimerizer, methotrexate

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