DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

Hiroki Kaneko; Sami Dridi; Valeria Tarallo; Bradley D. Gelfand; Benjamin J. Fowler; Won Gil Cho; Mark E. Kleinman; Steven L. Ponicsan; William W. Hauswirth; Vince A. Chiodo; Katalin Karikó; Jae Wook Yoo; Dong Ki Lee; Majda Hadziahmetovic; Ying Song; Smita Misra; Gautam Chaudhuri; Frank W. Buaas; Robert E. Braun; David R. Hinton; Qing Zhang; Hans E. Grossniklaus; Jan M. Provis; Michele C. Madigan; Ann H. Milam; Nikki L. Justice; Romulo J.C. Albuquerque; Alexander D. Blandford; Sasha Bogdanovich; Yoshio Hirano; Jassir Witta; Elaine Fuchs; Dan R. Littman; Balamurali K. Ambati; Charles M. Rudin; Mark M.W. Chong; Patrick Provost; Jennifer F. Kugel; James A. Goodrich; Joshua L. Dunaief; Judit Z. Baffi; Jayakrishna Ambati

doi:10.1038/nature09830

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

Hiroki Kaneko
, Sami Dridi
, Valeria Tarallo
, Bradley D. Gelfand
, Benjamin J. Fowler
, Won Gil Cho
, Mark E. Kleinman
, Steven L. Ponicsan
, William W. Hauswirth
, Vince A. Chiodo
, Katalin Karikó
, Jae Wook Yoo
, Dong Ki Lee
, Majda Hadziahmetovic
, Ying Song
, Smita Misra
, Gautam Chaudhuri
, Frank W. Buaas
, Robert E. Braun
, David R. Hinton

Qing Zhang, Hans E. Grossniklaus, Jan M. Provis, Michele C. Madigan, Ann H. Milam, Nikki L. Justice, Romulo J.C. Albuquerque, Alexander D. Blandford, Sasha Bogdanovich, Yoshio Hirano, Jassir Witta, Elaine Fuchs, Dan R. Littman, Balamurali K. Ambati, Charles M. Rudin, Mark M.W. Chong, Patrick Provost, Jennifer F. Kugel, James A. Goodrich, Joshua L. Dunaief, Judit Z. Baffi, Jayakrishna Ambati

Department of Surgery

University of Kentucky College of Medicine
Yonsei University Wonju College of Medicine
University of Colorado Boulder
University of Florida College of Medicine
University of Pennsylvania Perelman School of Medicine
Sungkyunkwan University
University of Pennsylvania
Meharry Medical College
Jackson Laboratory
University of Southern California
Emory University School of Medicine
Australian National University
University of New South Wales
Save Sight Institute
Rockefeller University
New York University School of Medicine
University of Utah Department of Radiology
Canandaigua VA Medical Center
Johns Hopkins University
Walter and Eliza Hall Institute of Medical Research
Université Laval

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	325-332
Number of pages	8
Journal	Nature
Volume	471
Issue number	7338
DOIs	https://doi.org/10.1038/nature09830
State	Published - Mar 17 2011

ASJC Scopus Subject Areas

General

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Kaneko, H., Dridi, S., Tarallo, V., Gelfand, B. D., Fowler, B. J., Cho, W. G., Kleinman, M. E., Ponicsan, S. L., Hauswirth, W. W., Chiodo, V. A., Karikó, K., Yoo, J. W., Lee, D. K., Hadziahmetovic, M., Song, Y., Misra, S., Chaudhuri, G., Buaas, F. W., Braun, R. E., ... Ambati, J. (2011). DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature, 471(7338), 325-332. https://doi.org/10.1038/nature09830

Kaneko, H, Dridi, S, Tarallo, V, Gelfand, BD, Fowler, BJ, Cho, WG, Kleinman, ME, Ponicsan, SL, Hauswirth, WW, Chiodo, VA, Karikó, K, Yoo, JW, Lee, DK, Hadziahmetovic, M, Song, Y, Misra, S, Chaudhuri, G, Buaas, FW, Braun, RE, Hinton, DR, Zhang, Q, Grossniklaus, HE, Provis, JM, Madigan, MC, Milam, AH, Justice, NL, Albuquerque, RJC, Blandford, AD, Bogdanovich, S, Hirano, Y, Witta, J, Fuchs, E, Littman, DR, Ambati, BK, Rudin, CM, Chong, MMW, Provost, P, Kugel, JF, Goodrich, JA, Dunaief, JL, Baffi, JZ & Ambati, J 2011, 'DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration', Nature, vol. 471, no. 7338, pp. 325-332. https://doi.org/10.1038/nature09830

@article{d4508f1c464446cdb4895d34f9b2959d,

title = "DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration",

author = "Hiroki Kaneko and Sami Dridi and Valeria Tarallo and Gelfand, \{Bradley D.\} and Fowler, \{Benjamin J.\} and Cho, \{Won Gil\} and Kleinman, \{Mark E.\} and Ponicsan, \{Steven L.\} and Hauswirth, \{William W.\} and Chiodo, \{Vince A.\} and Katalin Karik{\'o} and Yoo, \{Jae Wook\} and Lee, \{Dong Ki\} and Majda Hadziahmetovic and Ying Song and Smita Misra and Gautam Chaudhuri and Buaas, \{Frank W.\} and Braun, \{Robert E.\} and Hinton, \{David R.\} and Qing Zhang and Grossniklaus, \{Hans E.\} and Provis, \{Jan M.\} and Madigan, \{Michele C.\} and Milam, \{Ann H.\} and Justice, \{Nikki L.\} and Albuquerque, \{Romulo J.C.\} and Blandford, \{Alexander D.\} and Sasha Bogdanovich and Yoshio Hirano and Jassir Witta and Elaine Fuchs and Littman, \{Dan R.\} and Ambati, \{Balamurali K.\} and Rudin, \{Charles M.\} and Chong, \{Mark M.W.\} and Patrick Provost and Kugel, \{Jennifer F.\} and Goodrich, \{James A.\} and Dunaief, \{Joshua L.\} and Baffi, \{Judit Z.\} and Jayakrishna Ambati",

year = "2011",

month = mar,

day = "17",

doi = "10.1038/nature09830",

language = "English",

volume = "471",

pages = "325--332",

journal = "Nature",

issn = "0028-0836",

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TY - JOUR

T1 - DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

AU - Kaneko, Hiroki

AU - Dridi, Sami

AU - Tarallo, Valeria

AU - Gelfand, Bradley D.

AU - Fowler, Benjamin J.

AU - Cho, Won Gil

AU - Kleinman, Mark E.

AU - Ponicsan, Steven L.

AU - Hauswirth, William W.

AU - Chiodo, Vince A.

AU - Karikó, Katalin

AU - Yoo, Jae Wook

AU - Lee, Dong Ki

AU - Hadziahmetovic, Majda

AU - Song, Ying

AU - Misra, Smita

AU - Chaudhuri, Gautam

AU - Buaas, Frank W.

AU - Braun, Robert E.

AU - Hinton, David R.

AU - Zhang, Qing

AU - Grossniklaus, Hans E.

AU - Provis, Jan M.

AU - Madigan, Michele C.

AU - Milam, Ann H.

AU - Justice, Nikki L.

AU - Albuquerque, Romulo J.C.

AU - Blandford, Alexander D.

AU - Bogdanovich, Sasha

AU - Hirano, Yoshio

AU - Witta, Jassir

AU - Fuchs, Elaine

AU - Littman, Dan R.

AU - Ambati, Balamurali K.

AU - Rudin, Charles M.

AU - Chong, Mark M.W.

AU - Provost, Patrick

AU - Kugel, Jennifer F.

AU - Goodrich, James A.

AU - Dunaief, Joshua L.

AU - Baffi, Judit Z.

AU - Ambati, Jayakrishna

PY - 2011/3/17

Y1 - 2011/3/17

UR - https://www.scopus.com/pages/publications/79952786337

UR - https://www.scopus.com/pages/publications/79952786337#tab=citedBy

U2 - 10.1038/nature09830

DO - 10.1038/nature09830

M3 - Article

AN - SCOPUS:79952786337

SN - 0028-0836

VL - 471

SP - 325

EP - 332

JO - Nature

JF - Nature

IS - 7338

ER -

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

ASJC Scopus Subject Areas

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