Effect of 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2 (1H)-one (BMS-223131), a novel opener of large conductance Ca2+-activated K+ (maxi-K) channels on normal and stress-aggravated colonic motility and visceral nociception

Digavalli V Sivarao; Kimberly Newberry; S. Langdon; A.  Lee; P. Hewawasam; M. J. Plym; L. Signor; Robert Myers; Nicholas J. Lodge

Effect of 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2 (1H)-one (BMS-223131), a novel opener of large conductance Ca2+-activated K+ (maxi-K) channels on normal and stress-aggravated colonic motility and visceral nociception

Digavalli V Sivarao
, Kimberly Newberry
, S. Langdon
, A. Lee
, P. Hewawasam
, M. J. Plym
, L. Signor
, Robert Myers
, Nicholas J. Lodge

Department of Pharmaceutical Sciences

Bristol-Myers Squibb
Bristol-Myers Squibb Research and Development
NeurOp, Inc.

Research output: Contribution to journal › Article › peer-review

Original language	American English
Pages (from-to)	840-847
Number of pages	8
Journal	Journal of Pharmacology and Experimental Therapeutics
Volume	313
Issue number	2
State	Published - 2005

Cite this

Sivarao, D. V., Newberry, K., Langdon, S., Lee, A., Hewawasam, P., Plym, M. J., Signor, L., Myers, R., & Lodge, N. J. (2005). Effect of 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2 (1H)-one (BMS-223131), a novel opener of large conductance Ca2+-activated K+ (maxi-K) channels on normal and stress-aggravated colonic motility and visceral nociception. Journal of Pharmacology and Experimental Therapeutics, 313(2), 840-847.

Effect of 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2 (1H)-one (BMS-223131), a novel opener of large conductance Ca2+-activated K+ (maxi-K) channels on normal and stress-aggravated colonic motility and visceral nociception. / Sivarao, Digavalli V; Newberry, Kimberly; Langdon, S. et al.
In: Journal of Pharmacology and Experimental Therapeutics, Vol. 313, No. 2, 2005, p. 840-847.

Research output: Contribution to journal › Article › peer-review

Sivarao, DV, Newberry, K, Langdon, S, Lee, A, Hewawasam, P, Plym, MJ, Signor, L, Myers, R & Lodge, NJ 2005, 'Effect of 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2 (1H)-one (BMS-223131), a novel opener of large conductance Ca2+-activated K+ (maxi-K) channels on normal and stress-aggravated colonic motility and visceral nociception', Journal of Pharmacology and Experimental Therapeutics, vol. 313, no. 2, pp. 840-847.

Sivarao DV, Newberry K, Langdon S, Lee A, Hewawasam P, Plym MJ et al. Effect of 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2 (1H)-one (BMS-223131), a novel opener of large conductance Ca2+-activated K+ (maxi-K) channels on normal and stress-aggravated colonic motility and visceral nociception. Journal of Pharmacology and Experimental Therapeutics. 2005;313(2):840-847.

Sivarao, Digavalli V ; Newberry, Kimberly ; Langdon, S. et al. / Effect of 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2 (1H)-one (BMS-223131), a novel opener of large conductance Ca2+-activated K+ (maxi-K) channels on normal and stress-aggravated colonic motility and visceral nociception. In: Journal of Pharmacology and Experimental Therapeutics. 2005 ; Vol. 313, No. 2. pp. 840-847.

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title = "Effect of 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2 (1H)-one (BMS-223131), a novel opener of large conductance Ca2+-activated K+ (maxi-K) channels on normal and stress-aggravated colonic motility and visceral nociception",

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AU - Sivarao, Digavalli V

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AU - Lee, A.

AU - Hewawasam, P.

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AU - Myers, Robert

AU - Lodge, Nicholas J.

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