Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma

Qian Xie; Robert Bradley; Liang Kang; Julie Koeman; Maria Libera Ascierto; Andrea Worschech; Valeria De Giorgi; Ena Wang; Lisa Kefene; Yanli Su; Curt Essenburg; Dafna W. Kaufman; Tom DeKoning; Mark A. Enter; Timothy J. O'Rourke; Francesco M. Marincola; George F. Vande Woude

doi:10.1073/pnas.1119059109

Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma

Qian Xie
, Robert Bradley
, Liang Kang
, Julie Koeman
, Maria Libera Ascierto
, Andrea Worschech
, Valeria De Giorgi
, Ena Wang
, Lisa Kefene
, Yanli Su
, Curt Essenburg
, Dafna W. Kaufman
, Tom DeKoning
, Mark A. Enter
, Timothy J. O'Rourke
, Francesco M. Marincola
, George F. Vande Woude

Department of Biomedical Sciences

Van Andel Research Institute
National Institutes of Health (NIH)
Spectrum Health

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	570-575
Number of pages	6
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	109
Issue number	2
DOIs	https://doi.org/10.1073/pnas.1119059109
State	Published - Jan 10 2012

ASJC Scopus Subject Areas

General

Keywords

Hepatocyte growth factor-autocrine loop
Molecular marker
Oncogene addiction
Targeted therapy

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10.1073/pnas.1119059109

Cite this

Xie, Q., Bradley, R., Kang, L., Koeman, J., Ascierto, M. L., Worschech, A., De Giorgi, V., Wang, E., Kefene, L., Su, Y., Essenburg, C., Kaufman, D. W., DeKoning, T., Enter, M. A., O'Rourke, T. J., Marincola, F. M., & Vande Woude, G. F. (2012). Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma. Proceedings of the National Academy of Sciences of the United States of America, 109(2), 570-575. https://doi.org/10.1073/pnas.1119059109

Xie, Q, Bradley, R, Kang, L, Koeman, J, Ascierto, ML, Worschech, A, De Giorgi, V, Wang, E, Kefene, L, Su, Y, Essenburg, C, Kaufman, DW, DeKoning, T, Enter, MA, O'Rourke, TJ, Marincola, FM & Vande Woude, GF 2012, 'Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma', Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 2, pp. 570-575. https://doi.org/10.1073/pnas.1119059109

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author = "Qian Xie and Robert Bradley and Liang Kang and Julie Koeman and Ascierto, \{Maria Libera\} and Andrea Worschech and \{De Giorgi\}, Valeria and Ena Wang and Lisa Kefene and Yanli Su and Curt Essenburg and Kaufman, \{Dafna W.\} and Tom DeKoning and Enter, \{Mark A.\} and O'Rourke, \{Timothy J.\} and Marincola, \{Francesco M.\} and \{Vande Woude\}, \{George F.\}",

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AU - Bradley, Robert

AU - Kang, Liang

AU - Koeman, Julie

AU - Ascierto, Maria Libera

AU - Worschech, Andrea

AU - De Giorgi, Valeria

AU - Wang, Ena

AU - Kefene, Lisa

AU - Su, Yanli

AU - Essenburg, Curt

AU - Kaufman, Dafna W.

AU - DeKoning, Tom

AU - Enter, Mark A.

AU - O'Rourke, Timothy J.

AU - Marincola, Francesco M.

AU - Vande Woude, George F.

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KW - Molecular marker

KW - Oncogene addiction

KW - Targeted therapy

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Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma

ASJC Scopus Subject Areas

Keywords

Access to Document

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