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High-content analysis of constitutive androstane receptor (CAR) translocation identifies mosapride citrate as a CAR agonist that represses gluconeogenesis

  • Bryan Mackowiak
  • , Linhao Li
  • , Caitlin Lynch
  • , Andrew Ziman
  • , Scott Heyward
  • , Menghang Xia
  • , Hongbing Wang
  • University of Maryland School of Pharmacy
  • National Center for Advancing Translational Sciences (NCATS)
  • Nikon Instruments Inc.
  • Bioreclamation In Vitro Technologies

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)224-236
Number of pages13
JournalBiochemical Pharmacology
Volume168
DOIs
StatePublished - Oct 2019

ASJC Scopus Subject Areas

  • Biochemistry
  • Pharmacology

Keywords

  • CAR
  • Gluconeogenesis
  • High-content screening
  • Mosapride citrate
  • Nuclear translocation

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