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Machine learning-based prediction of enzyme substrate scope: Application to bacterial nitrilases

  • Zhongyu Mou
  • , Jason Eakes
  • , Connor J. Cooper
  • , Carmen M. Foster
  • , Robert F. Standaert
  • , Mircea Podar
  • , Mitchel J. Doktycz
  • , Jerry M. Parks
  • Oak Ridge National Laboratory
  • University of TennesseeWalters Life Science
  • Biosciences Division

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)336-347
Number of pages12
JournalProteins: Structure, Function and Bioinformatics
Volume89
Issue number3
DOIs
StatePublished - Mar 2021

ASJC Scopus Subject Areas

  • Structural Biology
  • Biochemistry
  • Molecular Biology

Keywords

  • enzyme specificity
  • functional annotation
  • machine learning
  • modular approach
  • substrate scope

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