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Phosphonic acid analogs of GABA through reductive dealkylation of phosphonic diesters with lithium trialkylborohydrides

  • Sarwat Chowdhury
  • , Niraj J. Muni
  • , Nicholas P. Greenwood
  • , David R. Pepperberg
  • , Robert F. Standaert
  • University of Illinois at Chicago
  • University of Illinois at Chicago
  • Biological and Nanoscale Systems Group (BNSG)
  • Oak Ridge National Laboratory

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)3745-3748
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume17
Issue number13
DOIs
StatePublished - Jul 1 2007

ASJC Scopus Subject Areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

Keywords

  • Dealkylation
  • GABA antagonists
  • GABA receptors
  • Lithium trialkylborohydrides
  • Phosphonate esters

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