Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction

Yu-Te Yeh; Chandan Sona; Xin Yan; Yunxiao Li; Adrija Pathak; Mark I. McDermott; Zhigang Xie; Liangwen Liu; Anoop Arunagiri; Yuting Wang; Amaury Cazenave-Gassiot; Adhideb Ghosh; Ferdinand Von Meyenn; Sivarajan Kumarasamy; Sonia M. Najjar; Shiqi Jia; Markus R. Wenk; Alexis Traynor-Kaplan; Peter Arvan; Sebastian Barg; Vytas A. Bankaitis; Matthew N. Poy

doi:10.1038/s41467-023-39978-1

Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction

Yu-Te Yeh
, Chandan Sona
, Xin Yan
, Yunxiao Li
, Adrija Pathak
, Mark I. McDermott
, Zhigang Xie
, Liangwen Liu
, Anoop Arunagiri
, Yuting Wang
, Amaury Cazenave-Gassiot
, Adhideb Ghosh
, Ferdinand Von Meyenn
, Sivarajan Kumarasamy
, Sonia M. Najjar
, Shiqi Jia
, Markus R. Wenk
, Alexis Traynor-Kaplan
, Peter Arvan
, Sebastian Barg

Vytas A. Bankaitis, Matthew N. Poy

Department of Biological Sciences

John Hopkins University
Max Delbruck Center for Molecular Medicine
University Medical Center Rostock
Texas A&M University
Uppsala University
National University of Singapore
ETH Zürich
Ohio University
The First Affiliated Hospital of Jinan University
University of Washington School of Medicine
University of Michigan, Ann Arbor

Research output: Contribution to journal › Article › peer-review

Original language	American English
Article number	4250
Journal	Nature Communications
Volume	14
Issue number	1
DOIs	https://doi.org/10.1038/s41467-023-39978-1
State	Published - Jul 17 2023

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10.1038/s41467-023-39978-1

Cite this

Yeh, Y.-T., Sona, C., Yan, X., Li, Y., Pathak, A., McDermott, M. I., Xie, Z., Liu, L., Arunagiri, A., Wang, Y., Cazenave-Gassiot, A., Ghosh, A., Von Meyenn, F., Kumarasamy, S., Najjar, S. M., Jia, S., Wenk, M. R., Traynor-Kaplan, A., Arvan, P., ... Poy, M. N. (2023). Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction. Nature Communications, 14(1), Article 4250. https://doi.org/10.1038/s41467-023-39978-1

Yeh, Y-T, Sona, C, Yan, X, Li, Y, Pathak, A, McDermott, MI, Xie, Z, Liu, L, Arunagiri, A, Wang, Y, Cazenave-Gassiot, A, Ghosh, A, Von Meyenn, F, Kumarasamy, S, Najjar, SM, Jia, S, Wenk, MR, Traynor-Kaplan, A, Arvan, P, Barg, S, Bankaitis, VA & Poy, MN 2023, 'Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction', Nature Communications, vol. 14, no. 1, 4250. https://doi.org/10.1038/s41467-023-39978-1

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title = "Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction",

author = "Yu-Te Yeh and Chandan Sona and Xin Yan and Yunxiao Li and Adrija Pathak and McDermott, \{Mark I.\} and Zhigang Xie and Liangwen Liu and Anoop Arunagiri and Yuting Wang and Amaury Cazenave-Gassiot and Adhideb Ghosh and \{Von Meyenn\}, Ferdinand and Sivarajan Kumarasamy and Najjar, \{Sonia M.\} and Shiqi Jia and Wenk, \{Markus R.\} and Alexis Traynor-Kaplan and Peter Arvan and Sebastian Barg and Bankaitis, \{Vytas A.\} and Poy, \{Matthew N.\}",

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T1 - Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction

AU - Yeh, Yu-Te

AU - Sona, Chandan

AU - Yan, Xin

AU - Li, Yunxiao

AU - Pathak, Adrija

AU - McDermott, Mark I.

AU - Xie, Zhigang

AU - Liu, Liangwen

AU - Arunagiri, Anoop

AU - Wang, Yuting

AU - Cazenave-Gassiot, Amaury

AU - Ghosh, Adhideb

AU - Von Meyenn, Ferdinand

AU - Kumarasamy, Sivarajan

AU - Najjar, Sonia M.

AU - Jia, Shiqi

AU - Wenk, Markus R.

AU - Traynor-Kaplan, Alexis

AU - Arvan, Peter

AU - Barg, Sebastian

AU - Bankaitis, Vytas A.

AU - Poy, Matthew N.

PY - 2023/7/17

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DO - 10.1038/s41467-023-39978-1

M3 - Article

SN - 2041-1723

VL - 14

JO - Nature Communications

JF - Nature Communications

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