Retrospective Cohort Study of the Efficacy of Azithromycin Vs. Doxycycline as Part of Combination Therapy in Non-Intensive Care Unit Veterans Hospitalized with Community-Acquired Pneumonia

Justin Spivey; Heather Sirek; Robert Wood; Kalpit Devani; Billy Brooks; Jonathan Moorman

doi:10.1093/ofid/ofx163.1513

Retrospective Cohort Study of the Efficacy of Azithromycin Vs. Doxycycline as Part of Combination Therapy in Non-Intensive Care Unit Veterans Hospitalized with Community-Acquired Pneumonia

Justin Spivey, Heather Sirek, Robert Wood, Kalpit Devani, Billy Brooks, Jonathan Moorman

Research output: Contribution to journal › Article › peer-review

Abstract

The IDSA Community-Acquired Pneumonia (CAP) Guideline recommends ceftriaxone in combination with doxycycline as an alternative to combination therapy with ceftriaxone and azithromycin for non-intensive care unit (ICU) patients hospitalized with CAP. This is an attractive alternative regimen due to recent concerns of increased cardiovascular risk associated with azithromycin. The objective of this study was to compare the clinical outcomes of azithromycin and doxycycline each in combination with ceftriaxone for non-ICU Veterans hospitalized with CAP.

Original language	American English
Journal	Open Forum Infectious Diseases
Volume	4
DOIs	https://doi.org/10.1093/ofid/ofx163.1513
State	Published - Oct 1 2017

Keywords

blood culture positive
cardiovascular disease risk factors
community acquired pneumonia
curb criteria
emergency service
hospital
infectious diseases society of america
inpatients
intensive care unit
patient readmission
pneumonia
treatment outcome
veterans

Disciplines

Community Health and Preventive Medicine

Access to Document

10.1093/ofid/ofx163.1513License: Unspecified

Retrospective Cohort Study of the Efficacy of Azithromycin VsFinal published version, 719 KBLicense: Unspecified

https://doi.org/10.1093/ofid/ofx163.1513

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title = "Retrospective Cohort Study of the Efficacy of Azithromycin Vs. Doxycycline as Part of Combination Therapy in Non-Intensive Care Unit Veterans Hospitalized with Community-Acquired Pneumonia",

abstract = " The IDSA Community-Acquired Pneumonia (CAP) Guideline recommends ceftriaxone in combination with doxycycline as an alternative to combination therapy with ceftriaxone and azithromycin for non-intensive care unit (ICU) patients hospitalized with CAP. This is an attractive alternative regimen due to recent concerns of increased cardiovascular risk associated with azithromycin. The objective of this study was to compare the clinical outcomes of azithromycin and doxycycline each in combination with ceftriaxone for non-ICU Veterans hospitalized with CAP.",

keywords = "blood culture positive, cardiovascular disease risk factors, community acquired pneumonia, curb criteria, emergency service, hospital, infectious diseases society of america, inpatients, intensive care unit, patient readmission, pneumonia, treatment outcome, veterans",

author = "Justin Spivey and Heather Sirek and Robert Wood and Kalpit Devani and Billy Brooks and Jonathan Moorman",

year = "2017",

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doi = "10.1093/ofid/ofx163.1513",

language = "American English",

volume = "4",

journal = "Open Forum Infectious Diseases",

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T1 - Retrospective Cohort Study of the Efficacy of Azithromycin Vs. Doxycycline as Part of Combination Therapy in Non-Intensive Care Unit Veterans Hospitalized with Community-Acquired Pneumonia

AU - Spivey, Justin

AU - Sirek, Heather

AU - Wood, Robert

AU - Devani, Kalpit

AU - Brooks, Billy

AU - Moorman, Jonathan

PY - 2017/10/1

Y1 - 2017/10/1

N2 - The IDSA Community-Acquired Pneumonia (CAP) Guideline recommends ceftriaxone in combination with doxycycline as an alternative to combination therapy with ceftriaxone and azithromycin for non-intensive care unit (ICU) patients hospitalized with CAP. This is an attractive alternative regimen due to recent concerns of increased cardiovascular risk associated with azithromycin. The objective of this study was to compare the clinical outcomes of azithromycin and doxycycline each in combination with ceftriaxone for non-ICU Veterans hospitalized with CAP.

AB - The IDSA Community-Acquired Pneumonia (CAP) Guideline recommends ceftriaxone in combination with doxycycline as an alternative to combination therapy with ceftriaxone and azithromycin for non-intensive care unit (ICU) patients hospitalized with CAP. This is an attractive alternative regimen due to recent concerns of increased cardiovascular risk associated with azithromycin. The objective of this study was to compare the clinical outcomes of azithromycin and doxycycline each in combination with ceftriaxone for non-ICU Veterans hospitalized with CAP.

KW - blood culture positive

KW - cardiovascular disease risk factors

KW - community acquired pneumonia

KW - curb criteria

KW - emergency service

KW - hospital

KW - infectious diseases society of america

KW - inpatients

KW - intensive care unit

KW - patient readmission

KW - pneumonia

KW - treatment outcome

KW - veterans

UR - https://dc.etsu.edu/etsu-works/3177

U2 - 10.1093/ofid/ofx163.1513

DO - 10.1093/ofid/ofx163.1513

M3 - Article

VL - 4

JO - Open Forum Infectious Diseases

JF - Open Forum Infectious Diseases

ER -

Retrospective Cohort Study of the Efficacy of Azithromycin Vs. Doxycycline as Part of Combination Therapy in Non-Intensive Care Unit Veterans Hospitalized with Community-Acquired Pneumonia

Abstract

Keywords

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