Telomeric injury by KML001 in human T cells induces mitochondrial dysfunction through the p53-PGC-1α pathway

Madison Schank; Juan Zhao; Ling Wang; Zhengke Li; Dechao Cao; Lam Nhat Nguyen; Xindi Dang; Sushant Khanal; Lam Ngoc Thao Nguyen; Bal Krishna Chand Thakuri; Stella C. Ogbu; Zeyuan Lu; Jinyu Zhang; Xiao Y. Wu; Zheng D. Morrison; Mohamed El Gazzar; Shunbin Ning; Jonathan P. Moorman; Zhi Q. Yao

doi:10.1038/s41419-020-03238-7

Telomeric injury by KML001 in human T cells induces mitochondrial dysfunction through the p53-PGC-1α pathway

Madison Schank
, Juan Zhao
, Ling Wang
, Zhengke Li
, Dechao Cao
, Lam Nhat Nguyen
, Xindi Dang
, Sushant Khanal
, Lam Ngoc Thao Nguyen
, Bal Krishna Chand Thakuri
, Stella C. Ogbu
, Zeyuan Lu
, Jinyu Zhang
, Xiao Y. Wu
, Zheng D. Morrison
, Mohamed El Gazzar
, Shunbin Ning
, Jonathan P. Moorman
, Zhi Q. Yao

Quillen College of Medicine

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	1030
Journal	Cell Death and Disease
Volume	11
Issue number	12
DOIs	https://doi.org/10.1038/s41419-020-03238-7
State	Published - Dec 2020

ASJC Scopus Subject Areas

Immunology
Cellular and Molecular Neuroscience
Cell Biology
Cancer Research

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10.1038/s41419-020-03238-7

Cite this

Schank, M., Zhao, J., Wang, L., Li, Z., Cao, D., Nguyen, L. N., Dang, X., Khanal, S., Nguyen, L. N. T., Thakuri, B. K. C., Ogbu, S. C., Lu, Z., Zhang, J., Wu, X. Y., Morrison, Z. D., El Gazzar, M., Ning, S., Moorman, J. P., & Yao, Z. Q. (2020). Telomeric injury by KML001 in human T cells induces mitochondrial dysfunction through the p53-PGC-1α pathway. Cell Death and Disease, 11(12), Article 1030. https://doi.org/10.1038/s41419-020-03238-7

Schank, M , Zhao, J , Wang, L, Li, Z, Cao, D, Nguyen, LN, Dang, X, Khanal, S, Nguyen, LNT, Thakuri, BKC, Ogbu, SC, Lu, Z, Zhang, J, Wu, XY, Morrison, ZD, El Gazzar, M, Ning, S , Moorman, JP & Yao, ZQ 2020, 'Telomeric injury by KML001 in human T cells induces mitochondrial dysfunction through the p53-PGC-1α pathway', Cell Death and Disease, vol. 11, no. 12, 1030. https://doi.org/10.1038/s41419-020-03238-7

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title = "Telomeric injury by KML001 in human T cells induces mitochondrial dysfunction through the p53-PGC-1α pathway",

author = "Madison Schank and Juan Zhao and Ling Wang and Zhengke Li and Dechao Cao and Nguyen, \{Lam Nhat\} and Xindi Dang and Sushant Khanal and Nguyen, \{Lam Ngoc Thao\} and Thakuri, \{Bal Krishna Chand\} and Ogbu, \{Stella C.\} and Zeyuan Lu and Jinyu Zhang and Wu, \{Xiao Y.\} and Morrison, \{Zheng D.\} and \{El Gazzar\}, Mohamed and Shunbin Ning and Moorman, \{Jonathan P.\} and Yao, \{Zhi Q.\}",

note = "Publisher Copyright: {\textcopyright} 2020, The Author(s).",

year = "2020",

month = dec,

doi = "10.1038/s41419-020-03238-7",

language = "English",

volume = "11",

journal = "Cell Death and Disease",

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TY - JOUR

T1 - Telomeric injury by KML001 in human T cells induces mitochondrial dysfunction through the p53-PGC-1α pathway

AU - Schank, Madison

AU - Zhao, Juan

AU - Wang, Ling

AU - Li, Zhengke

AU - Cao, Dechao

AU - Nguyen, Lam Nhat

AU - Dang, Xindi

AU - Khanal, Sushant

AU - Nguyen, Lam Ngoc Thao

AU - Thakuri, Bal Krishna Chand

AU - Ogbu, Stella C.

AU - Lu, Zeyuan

AU - Zhang, Jinyu

AU - Wu, Xiao Y.

AU - Morrison, Zheng D.

AU - El Gazzar, Mohamed

AU - Ning, Shunbin

AU - Moorman, Jonathan P.

AU - Yao, Zhi Q.

PY - 2020/12

Y1 - 2020/12

UR - https://www.scopus.com/pages/publications/85097026379

UR - https://www.scopus.com/pages/publications/85097026379#tab=citedBy

U2 - 10.1038/s41419-020-03238-7

DO - 10.1038/s41419-020-03238-7

M3 - Article

C2 - 33268822

AN - SCOPUS:85097026379

SN - 2041-4889

VL - 11

JO - Cell Death and Disease

JF - Cell Death and Disease

IS - 12

M1 - 1030

ER -

Telomeric injury by KML001 in human T cells induces mitochondrial dysfunction through the p53-PGC-1α pathway

ASJC Scopus Subject Areas

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