The Effects of Platelet-Activating Factor on the Motility of Human Spermatozoa

D. D. Ricker; B. S. Minhas; R. Kumar; J. L. Robertson; M. G. Dodson; Julie Bowers

doi:10.1016/S0015-0282(16)60981-0

The Effects of Platelet-Activating Factor on the Motility of Human Spermatozoa

D. D. Ricker
, B. S. Minhas
, R. Kumar
, J. L. Robertson
, M. G. Dodson
, Julie Bowers

Department of Biomedical Health Sciences

Quillen-Dishner College of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Our laboratory has recently detected the presence of platelet-activating factor (PAF)-like activity in human spermatozoa. To gain further insight into the role of PAF on the male reproductive system, this study, using videomicroscopy, evaluated the effects of synthetic PAF on the motility of human spermatozoa. Treatment of 20 human semen samples with 3.69 x 10-7 to 3.69 x 10-13 M PAF resulted in statistically significant increases in motility. Treatment of spermatozoa with lyso-PAF (the biologically inactive form of PAF) showed no change in motility. Treatment of spermatozoa with PAF in severely asthenozoospermic males may be of therapeutic value.

Original language	American English
Journal	Fertility and Sterility
Volume	52
DOIs	https://doi.org/10.1016/S0015-0282(16)60981-0
State	Published - Jan 1 1989

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title = "The Effects of Platelet-Activating Factor on the Motility of Human Spermatozoa",

abstract = " Our laboratory has recently detected the presence of platelet-activating factor (PAF)-like activity in human spermatozoa. To gain further insight into the role of PAF on the male reproductive system, this study, using videomicroscopy, evaluated the effects of synthetic PAF on the motility of human spermatozoa. Treatment of 20 human semen samples with 3.69 x 10-7 to 3.69 x 10-13 M PAF resulted in statistically significant increases in motility. Treatment of spermatozoa with lyso-PAF (the biologically inactive form of PAF) showed no change in motility. Treatment of spermatozoa with PAF in severely asthenozoospermic males may be of therapeutic value.",

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AU - Minhas, B. S.

AU - Kumar, R.

AU - Robertson, J. L.

AU - Dodson, M. G.

AU - Bowers, Julie

PY - 1989/1/1

Y1 - 1989/1/1

N2 - Our laboratory has recently detected the presence of platelet-activating factor (PAF)-like activity in human spermatozoa. To gain further insight into the role of PAF on the male reproductive system, this study, using videomicroscopy, evaluated the effects of synthetic PAF on the motility of human spermatozoa. Treatment of 20 human semen samples with 3.69 x 10-7 to 3.69 x 10-13 M PAF resulted in statistically significant increases in motility. Treatment of spermatozoa with lyso-PAF (the biologically inactive form of PAF) showed no change in motility. Treatment of spermatozoa with PAF in severely asthenozoospermic males may be of therapeutic value.

AB - Our laboratory has recently detected the presence of platelet-activating factor (PAF)-like activity in human spermatozoa. To gain further insight into the role of PAF on the male reproductive system, this study, using videomicroscopy, evaluated the effects of synthetic PAF on the motility of human spermatozoa. Treatment of 20 human semen samples with 3.69 x 10-7 to 3.69 x 10-13 M PAF resulted in statistically significant increases in motility. Treatment of spermatozoa with lyso-PAF (the biologically inactive form of PAF) showed no change in motility. Treatment of spermatozoa with PAF in severely asthenozoospermic males may be of therapeutic value.

UR - https://dc.etsu.edu/etsu-works/11753

UR - https://doi.org/10.1016/S0015-0282(16)60981-0

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M3 - Article

VL - 52

JO - Fertility and Sterility

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ER -

The Effects of Platelet-Activating Factor on the Motility of Human Spermatozoa

Abstract

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