Unravelling the anti-cancer mechanisms elicited by non-covalent thioredoxin reductase inhibitors for triple negative breast cancer therapy

Abigail Rullo; Brenna Flowers; Keacha Chang; An Zhang; Valentina Z. Petukhova; Luke Harding; Sammy Y. Aboagye; Maurizio Bocchetta; Wei Qiu; David L. Williams; Francesco Angelucci; Pavel A. Petukhov; Irida Kastrati

doi:10.1016/j.redox.2025.103980

Unravelling the anti-cancer mechanisms elicited by non-covalent thioredoxin reductase inhibitors for triple negative breast cancer therapy

Abigail Rullo
, Brenna Flowers
, Keacha Chang
, An Zhang
, Valentina Z. Petukhova
, Luke Harding
, Sammy Y. Aboagye
, Maurizio Bocchetta
, Wei Qiu
, David L. Williams
, Francesco Angelucci
, Pavel A. Petukhov
, Irida Kastrati

Department of Surgery

Loyola University Chicago
University of Illinois at Chicago
Rush University Medical Center
Università dell'Aquila

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	103980
Journal	Redox Biology
Volume	90
DOIs	https://doi.org/10.1016/j.redox.2025.103980
State	Published - Mar 2026

ASJC Scopus Subject Areas

Organic Chemistry

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10.1016/j.redox.2025.103980

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Rullo, A., Flowers, B., Chang, K., Zhang, A., Petukhova, V. Z., Harding, L., Aboagye, S. Y., Bocchetta, M., Qiu, W., Williams, D. L., Angelucci, F., Petukhov, P. A., & Kastrati, I. (2026). Unravelling the anti-cancer mechanisms elicited by non-covalent thioredoxin reductase inhibitors for triple negative breast cancer therapy. Redox Biology, 90, Article 103980. https://doi.org/10.1016/j.redox.2025.103980

Rullo, A, Flowers, B, Chang, K, Zhang, A, Petukhova, VZ, Harding, L, Aboagye, SY, Bocchetta, M, Qiu, W, Williams, DL, Angelucci, F, Petukhov, PA & Kastrati, I 2026, 'Unravelling the anti-cancer mechanisms elicited by non-covalent thioredoxin reductase inhibitors for triple negative breast cancer therapy', Redox Biology, vol. 90, 103980. https://doi.org/10.1016/j.redox.2025.103980

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title = "Unravelling the anti-cancer mechanisms elicited by non-covalent thioredoxin reductase inhibitors for triple negative breast cancer therapy",

author = "Abigail Rullo and Brenna Flowers and Keacha Chang and An Zhang and Petukhova, \{Valentina Z.\} and Luke Harding and Aboagye, \{Sammy Y.\} and Maurizio Bocchetta and Wei Qiu and Williams, \{David L.\} and Francesco Angelucci and Petukhov, \{Pavel A.\} and Irida Kastrati",

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year = "2026",

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doi = "10.1016/j.redox.2025.103980",

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AU - Rullo, Abigail

AU - Flowers, Brenna

AU - Chang, Keacha

AU - Zhang, An

AU - Petukhova, Valentina Z.

AU - Harding, Luke

AU - Aboagye, Sammy Y.

AU - Bocchetta, Maurizio

AU - Qiu, Wei

AU - Williams, David L.

AU - Angelucci, Francesco

AU - Petukhov, Pavel A.

AU - Kastrati, Irida

PY - 2026/3

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JO - Redox Biology

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Unravelling the anti-cancer mechanisms elicited by non-covalent thioredoxin reductase inhibitors for triple negative breast cancer therapy

ASJC Scopus Subject Areas

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